When taking MAOIs, which foods should be avoided?

When taking monoamine oxidase inhibitors (MAOIs), it is crucial to avoid foods that are high in tyramine. Tyramine is an amino acid that can cause dangerous increases in blood pressure when consumed in significant amounts in combination with MAOIs. The use of these medications inhibits the breakdown of tyramine, leading to a hypertensive crisis.

Cheddar cheese is a well-known source of tyramine, particularly aged cheeses, and the same applies to other fermented or aged foods. Foods such as certain cured meats, pickled products, and some alcoholic beverages also contain high levels of tyramine. For this reason, individuals on MAOIs must be vigilant about their diet and avoid these specific foods to prevent severe adverse reactions.

Other food choices presented may not contain significant levels of tyramine, making them safer options for individuals taking MAOIs. This emphasis on avoiding high-tyramine foods is critical for managing the safety and efficacy of the medication therapy.